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Anti-Haptoglobin Antibody
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Catalog No. T9901A-1454 Copy Product Info
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Anti-Haptoglobin Antibody is a humanized monoclonal antibody expressed in CHO cells targeting Haptoglobin (HP). This product, featuring a huIgG1 heavy chain and a hukappa light chain, has a predicted molecular weight of 150 kDa. It binds specifically to Haptoglobin with high affinity, blocking its interaction with free hemoglobin (Hb) or damage-associated molecular patterns (DAMPs, such as HMGB1). By interfering with HP-mediated ligand clearance mechanisms (e.g., the CD163 pathway), the antibody inhibits its anti-inflammatory or immunomodulatory functions. It serves as an important pharmacological tool for researching hemolytic diseases, acute phase responses, and the tumor immune microenvironment.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Antibody Information
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| Description | Anti-Haptoglobin Antibody is a humanized monoclonal antibody expressed in CHO cells targeting Haptoglobin (HP). This product, featuring a huIgG1 heavy chain and a hukappa light chain, has a predicted molecular weight of 150 kDa. It binds specifically to Haptoglobin with high affinity, blocking its interaction with free hemoglobin (Hb) or damage-associated molecular patterns (DAMPs, such as HMGB1). By interfering with HP-mediated ligand clearance mechanisms (e.g., the CD163 pathway), the antibody inhibits its anti-inflammatory or immunomodulatory functions. It serves as an important pharmacological tool for researching hemolytic diseases, acute phase responses, and the tumor immune microenvironment. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | Haptoglobin |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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