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Anti-CD151 Antibody is a potent monoclonal antibody targeting the transmembrane protein CD151, acting by disrupting its interaction with partner molecules such as integrins. The compound is an essential tool for investigating CD151-mediated intracellular signaling, tumor cell motility, and tissue remodeling mechanisms, aiming to inhibit the invasive phenotype of malignant cells by blocking the formation of tetraspanin-enriched microdomains.

| Description | Anti-CD151 Antibody is a potent monoclonal antibody targeting the transmembrane protein CD151, acting by disrupting its interaction with partner molecules such as integrins. The compound is an essential tool for investigating CD151-mediated intracellular signaling, tumor cell motility, and tissue remodeling mechanisms, aiming to inhibit the invasive phenotype of malignant cells by blocking the formation of tetraspanin-enriched microdomains. |
| In vitro | In tumor cell and endothelium co-culture assays, Anti-CD151 Antibody blocked CD151-mediated communication and inhibited tumor cell-induced tube formation [1]. |
| In vivo | In tumor xenograft models, systemic administration of Anti-CD151 Antibody significantly reduced tumorigenesis and inhibited angiogenesis [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD151 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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