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Theleganbanin B
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Catalog No. TN10921Cas No. 31554-34-4
Theleganbanin B is a p-terphenyl derivative discovered in the mushroom (Thelephora ganbajun). It inhibits the production of TNF-α, IL-6, and IL-1β in BV-2 microglial cells induced by LPS. Theleganbanin B also suppresses the phosphorylation of JAK2/STAT3 and holds potential for neurodegenerative disease research.
Theleganbanin B
😃Good
Catalog No. TN10921Cas No. 31554-34-4
Theleganbanin B is a p-terphenyl derivative discovered in the mushroom (Thelephora ganbajun). It inhibits the production of TNF-α, IL-6, and IL-1β in BV-2 microglial cells induced by LPS. Theleganbanin B also suppresses the phosphorylation of JAK2/STAT3 and holds potential for neurodegenerative disease research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Theleganbanin B is a p-terphenyl derivative discovered in the mushroom (Thelephora ganbajun). It inhibits the production of TNF-α, IL-6, and IL-1β in BV-2 microglial cells induced by LPS. Theleganbanin B also suppresses the phosphorylation of JAK2/STAT3 and holds potential for neurodegenerative disease research. |
| Molecular Weight | 424.40 |
| Formula | C26H16O6 |
| Cas No. | 31554-34-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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