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Veltuzumab
🥰Excellent
Catalog No. T76765Cas No. 728917-18-8
Alias IMMU-106, IMMU106, hA20
Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that displays anti-proliferative, apoptotic, and antibody-dependent cytotoxic effects in vitro and inhibits tumor growth in mice harboring human lymphomas, and is indicated for use in non-Hodgkin's lymphoma (NHL).
Veltuzumab
Veltuzumab
🥰Excellent
Purity: 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)
Catalog No. T76765Alias IMMU-106, IMMU106, hA20Cas No. 728917-18-8
Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that displays anti-proliferative, apoptotic, and antibody-dependent cytotoxic effects in vitro and inhibits tumor growth in mice harboring human lymphomas, and is indicated for use in non-Hodgkin's lymphoma (NHL).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $197 | In Stock | |
| 5 mg | $463 | In Stock | |
| 10 mg | $742 | In Stock | |
| 25 mg | $1,120 | In Stock | |
| 50 mg | $1,490 | In Stock |
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Concentration:7.81 mg/mL
Purity:97.7% (SDS-PAGE); 97.9% (SEC-HPLC)
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Product Introduction
Bioactivity
Chemical Properties
| Description | Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that displays anti-proliferative, apoptotic, and antibody-dependent cytotoxic effects in vitro and inhibits tumor growth in mice harboring human lymphomas, and is indicated for use in non-Hodgkin's lymphoma (NHL). |
| Targets&IC50 | Daudi cells:0.08-0.09 μg/mL (EC50) |
| In vitro | Veltuzumab was effective in reducing dissociation rates in human lymphoma cell lines and enhancing complement-dependent cytotoxicity in 1 of 3 cell lines, but did not exhibit other significant in vitro differences. [1] Veltuzumab (0.001-10 μg/mL, 3 hours) had low EC50 values ranging from 0.08-0.09 μg/mL in Daudi cell lines. [1] |
| In vivo | Veltuzumab (intravenous or subcutaneous; 5, 20, and 60 μg; single dose) achieves control of tumor growth, or removal of circulating and adherent B cells, at low doses in mouse models. [1] Veltuzumab (intraperitoneal; 0.05-35 μg) demonstrated significant efficacy in in vivo studies. [1] |
| Synonyms | IMMU-106, IMMU106, hA20 |
| Cas No. | 728917-18-8 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: buy Veltuzumab | purchase Veltuzumab | Veltuzumab cost | order Veltuzumab | Veltuzumab in vivo | Veltuzumab in vitro
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