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Foxy-5 Ammonium Salt
🥰Excellent
Catalog No. TP1565L1
Alias Foxy-5 Ammonium Salt(881188-51-8 Free base)
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and inhibits migration and invasion of epithelial cancer cells.Foxy-5 Foxy-5 Ammonium Salt effectively reduces the metastatic spread of prostate cancer cells with low WNT5A expression in an in situ mouse model.
Foxy-5 Ammonium Salt
🥰Excellent
Purity: 97.70%
Catalog No. TP1565L1Alias Foxy-5 Ammonium Salt(881188-51-8 Free base)
Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and inhibits migration and invasion of epithelial cancer cells.Foxy-5 Foxy-5 Ammonium Salt effectively reduces the metastatic spread of prostate cancer cells with low WNT5A expression in an in situ mouse model.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $97 | - | In Stock | |
| 5 mg | $319 | - | In Stock | |
| 10 mg | $478 | - | In Stock | |
| 25 mg | $783 | - | In Stock | |
| 50 mg | $1,090 | - | In Stock | |
| 100 mg | $1,470 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $343 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.70%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and inhibits migration and invasion of epithelial cancer cells.Foxy-5 Foxy-5 Ammonium Salt effectively reduces the metastatic spread of prostate cancer cells with low WNT5A expression in an in situ mouse model. |
| In vitro | Foxy-5 Ammonium Salt reduces the number of colonic cancer stem cells in a xenograft mouse model of human colonic cancer.[2] Foxy-5 Ammonium Salt effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model.[1] |
| Synonyms | Foxy-5 Ammonium Salt(881188-51-8 Free base) |
| Molecular Weight | 712.26 |
| Formula | C26H46N7O12S2 |
| Smiles | CSCC[C@H](NC=O)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CS)C(N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O.[NH4+] |
| Color | White |
| Appearance | Solid |
| Sequence | For-Met-Asp-Gly-Cys-Glu-Leu-OH |
| Sequence Short | MDGCEL |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (140.4 mM), Sonication is recommended.  H2O: 6.66 mg/mL (9.35 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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