Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 125.00 | |
50 μg | 35 days | $ 225.00 | |
100 μg | 35 days | $ 428.00 | |
500 μg | 35 days | $ 1,860.00 |
Description | (±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619. |
Synonyms | (±)13,14-Epoxydocosatrienoic Acid, (±)13,14-EpDoTrE, (±)-Dihomo-13,14-EET |
Molecular Weight | 348.50 |
Formula | C22H36O3 |
CAS No. | 355016-19-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 1 mg/ml
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(±)13,14-EDT 355016-19-2 (±)13,14-Epoxydocosatrienoic Acid (±)13,14-EpDoTrE (±)-Dihomo-13,14-EET inhibitor inhibit