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Anti-Dysadherin Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human dysadherin protein, also known as FXYD5, with exceptional binding affinity and selectivity, effectively facilitating the measurable detection and neutralization of this force-transducing glycoprotein across various preclinical experimental models to evaluate the disruption of actomyosin-mediated contractility during strictly monitored laboratory observation periods.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | Anti-Dysadherin Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human dysadherin protein, also known as FXYD5, with exceptional binding affinity and selectivity, effectively facilitating the measurable detection and neutralization of this force-transducing glycoprotein across various preclinical experimental models to evaluate the disruption of actomyosin-mediated contractility during strictly monitored laboratory observation periods. |
| In vitro | In colorectal cancer cell assays, Anti-Dysadherin Antibody blocked dysadherin-mediated mechanical forces and significantly inhibited cell motility and invasion [1]. |
| In vivo | In colorectal cancer models, systemic administration of Anti-Dysadherin Antibody reduced primary tumor volume and decreased the frequency of distant metastasis [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | Dysadherin |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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