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Theralizumab (Synonyms: TGN1412, TABO8, TAB-08)

Catalog No. T77093 Copy Product Info
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Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.

Theralizumab

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Catalog No. T77093
Synonyms TGN1412, TABO8, TAB-08

Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.

Theralizumab
Cas No. 906068-56-2
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$745In StockIn Stock
5 mg$1,980In StockIn Stock
10 mg$3,330-In Stock
25 mg$4,970-In Stock
50 mg$6,680-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.46% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.
SynonymsTGN1412, TABO8, TAB-08
Reactivity
Human
Verified Activity
Immobilized Human CD28 Protein (His) (TMPJ-00103) at 1 μg/mL (100 μL/well) can bind Theralizumab. The EC50 is 43.82 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD28
Chemical Properties
Molecular Weight145.62 kDa
Cas No.906068-56-2
Antibody Information
IsotypeHuman IgG4 kappa
Recommended Isotype Control
Storage & Solubility Information
Storage-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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