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Theralizumab (Synonyms: TGN1412, TABO8, TAB-08)

Catalog No. T77093 Copy Product Info
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Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.

Theralizumab

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Catalog No. T77093
Synonyms TGN1412, TABO8, TAB-08

Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.

Theralizumab
Cas No. 906068-56-2
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$745In StockIn Stock
5 mg$1,980In StockIn Stock
10 mg$3,330-In Stock
25 mg$4,970-In Stock
50 mg$6,680-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.46% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Theralizumab (TGN1412) is an anti-CD28-targeting monoclonal antibody that directly stimulates T cells. Theralizumab has antitumor activity and is used for the treatment of B-cell chronic lymphocytic leukemia and rheumatoid arthritis.
SynonymsTGN1412, TABO8, TAB-08
Reactivity
Human
Verified Activity
Immobilized Human CD28 Protein (His) (TMPJ-00103) at 1 μg/mL (100 μL/well) can bind Theralizumab. The EC50 is 43.82 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCD28
Chemical Properties
Molecular Weight145.62 kDa
Cas No.906068-56-2
Antibody Information
IsotypeHuman IgG4 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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