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VX5 (Synonyms: VX5/5261)
Catalog No. T9901A-1765 Copy Product Info
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VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting BCA-1/CXCL13. It significantly inhibits human CXCL13-mediated CXCR5 internalization and blocks the CXCL13-dependent chemotaxis and migration of both human and mouse B cells (with EC50 values of 105 nM for human tonsil cells and 253 nM for pre-B-697-hCXCR5 cells). VX5 is applicable in the study of autoimmune diseases such as multiple sclerosis and arthritis, as well as cancers like gastric lymphoma and colon cancer.
VX5
Copy Product Info🥰Excellent
Catalog No. T9901A-1765
Synonyms VX5/5261
VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting BCA-1/CXCL13. It significantly inhibits human CXCL13-mediated CXCR5 internalization and blocks the CXCL13-dependent chemotaxis and migration of both human and mouse B cells (with EC50 values of 105 nM for human tonsil cells and 253 nM for pre-B-697-hCXCR5 cells). VX5 is applicable in the study of autoimmune diseases such as multiple sclerosis and arthritis, as well as cancers like gastric lymphoma and colon cancer.
VX5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting BCA-1/CXCL13. It significantly inhibits human CXCL13-mediated CXCR5 internalization and blocks the CXCL13-dependent chemotaxis and migration of both human and mouse B cells (with EC50 values of 105 nM for human tonsil cells and 253 nM for pre-B-697-hCXCR5 cells). VX5 is applicable in the study of autoimmune diseases such as multiple sclerosis and arthritis, as well as cancers like gastric lymphoma and colon cancer. |
| Synonyms | VX5/5261 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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