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Aspergillumarin A is a dihydroisocoumarin derivative with various biological activities. It inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 liver cancer cells. Aspergillumarin A exhibits mild antibacterial activity against Staphylococcus aureus and Bacillus subtilis. This compound is applicable for hepatocellular carcinoma (HCC) research.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Aspergillumarin A is a dihydroisocoumarin derivative with various biological activities. It inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 liver cancer cells. Aspergillumarin A exhibits mild antibacterial activity against Staphylococcus aureus and Bacillus subtilis. This compound is applicable for hepatocellular carcinoma (HCC) research. |
| In vitro | Aspergillumarin A (50 μg/mL) shows mild antibacterial activity against Staphylococcus aureus and Bacillus subtilis. Furthermore, Aspergillumarin A (200 μM) significantly inhibits the proliferation of HepG2 liver cancer cells by inducing cell cycle arrest at the G0/G1 phase. |
| Molecular Weight | 248.28 |
| Formula | C14H16O4 |
| Cas No. | 1392495-06-5 |
| Smiles | O=C1C=2C(C[C@@H](CCCC(C)=O)O1)=CC=CC2O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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