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P-gp inhibitor 24 (Compound 10) is an inhibitor of P-glycoprotein (P-gp) that blocks P-gp-mediated efflux of fluorescent dyes. This compound is effective in reversing multidrug resistance (MDR) and can enhance the cytotoxic effects of Vincristine and Etoposide on cancer cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | P-gp inhibitor 24 (Compound 10) is an inhibitor of P-glycoprotein (P-gp) that blocks P-gp-mediated efflux of fluorescent dyes. This compound is effective in reversing multidrug resistance (MDR) and can enhance the cytotoxic effects of Vincristine and Etoposide on cancer cells. |
| Formula | C39H29N5O4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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