Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM). ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 113.00 | |
5 mg | In stock | $ 263.00 | |
10 mg | In stock | $ 343.00 | |
25 mg | In stock | $ 579.00 | |
50 mg | In stock | $ 829.00 | |
100 mg | In stock | $ 1,150.00 | |
500 mg | In stock | $ 2,280.00 |
Description | ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM). ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells. |
Targets&IC50 | RORγ:1.1 μM |
Molecular Weight | 441.52 |
Formula | C25H31NO6 |
CAS No. | 1334526-14-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 39.8 mg/mL (90.0 mM)
You can also refer to dose conversion for different animals. More
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ML 209 1334526-14-5 Metabolism ROR ML209 ML-209 inhibitor inhibit