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Quercetin 3-O-robinobioside

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Catalog No. TN2128Cas No. 52525-35-6

Quercetin 3-O-robinobioside is a quercetin-derived flavonol that exhibits strong antioxidant properties and demonstrates in vitro inhibitory activity against leukemia K562 cells, Quercetin 3-O-robinobioside supports cancer biology, oxidative stress research, as well as natural product-based drug discovery focused on antiproliferative and cytoprotective mechanisms.

Quercetin 3-O-robinobioside

Quercetin 3-O-robinobioside

Copy Product Info
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Catalog No. TN2128Cas No. 52525-35-6
Quercetin 3-O-robinobioside is a quercetin-derived flavonol that exhibits strong antioxidant properties and demonstrates in vitro inhibitory activity against leukemia K562 cells, Quercetin 3-O-robinobioside supports cancer biology, oxidative stress research, as well as natural product-based drug discovery focused on antiproliferative and cytoprotective mechanisms.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$198-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Quercetin 3-O-robinobioside is a quercetin-derived flavonol that exhibits strong antioxidant properties and demonstrates in vitro inhibitory activity against leukemia K562 cells, Quercetin 3-O-robinobioside supports cancer biology, oxidative stress research, as well as natural product-based drug discovery focused on antiproliferative and cytoprotective mechanisms.
In vitro
The chemical constituents of Leonurus heterophyllus were separated and purified by repeated column chromatography on silica gel, HPD 100, Sephadex LH-20, and PHPLC. Each compound was characterized by spectroscopic and physical data. Eight compounds have been purified and identified to be Quercetin 3-O-robinobioside (1), rutin (2), isoquerci trin (3), hyperoside (4), quercetin (5), apigenin (6), genkwanin (7), and benzoic acid (8). Among them, compounds 2, 5-7 were isolated from L. heterophyllus for the first time; Compounds 1, 3, 4, 8 were obtained for the first time from the genus Leonurus. The in vitro activities against leukemia K562 Cells of pure components were evaluated by testing their IC50.
Chemical Properties
Molecular Weight610.52
FormulaC27H30O16
Cas No.52525-35-6
SmilesO(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC(O)=C(O)C=C3)[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@H](O)[C@H](O)[C@H]4O
Relative Density.1.82 g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (131.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6379 mL8.1897 mL16.3795 mL81.8974 mL
5 mM0.3276 mL1.6379 mL3.2759 mL16.3795 mL
10 mM0.1638 mL0.8190 mL1.6379 mL8.1897 mL
20 mM0.0819 mL0.4095 mL0.8190 mL4.0949 mL
50 mM0.0328 mL0.1638 mL0.3276 mL1.6379 mL
100 mM0.0164 mL0.0819 mL0.1638 mL0.8190 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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