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Synonyms: PIG61, NISBD2, mENA, LEGFR, HER1, ERBB1, ErbB, ERBB, EGFR, EC 2.7.10.1, EC 2.7.10


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $286 | 7-10 days | 7-10 days | |
| 20 µg | $448 | 7-10 days | 7-10 days | |
| 50 µg | $829 | 7-10 days | 7-10 days | |
| 100 µg | $1,320 | 7-10 days | 7-10 days | |
| 200 µg | $2,090 | 7-10 days | 7-10 days | |
| 500 µg | $3,920 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 50.3 ng/ml determined by ELISA. |
| Description | HLA-A*11:01&B2M&EGFR L858R (KITDFGRAK) Tetramer Protein, Human, MHC (His & Avi) is expressed in HEK293 Cells. The accession number is AAV53343.1(HLA-A*11:01)&P61769(B2M)&KITDFGRAK. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | AAV53343.1(HLA-A*11:01)&P61769(B2M)&KITDFGRAK |
| Construction | Gly25-Thr305(HLA-A*11:01), Ile21-Met119 (B2M) and KITDFGRAK peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | PIG61, NISBD2, mENA, LEGFR, HER1, ERBB1, ErbB, ERBB, EGFR, EC 2.7.10.1, EC 2.7.10 |
| Research Background | The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. |
| Molecular Weight | 201.60 kDa (Predicted); 205-220 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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