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Regn5678
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Catalog No. T9901A-793Cas No. 2657613-60-8
Alias Regn5678 (Anti-CD28 & PSMA), Regn5678, Nezastomig
REGN5678 is a bispecific antibody that targets both PSMA on prostate cancer cells and CD28 on T cells, enhancing immune activation. This drug is being developed to treat prostate cancer by redirecting T cells to tumors expressing PSMA, thereby promoting tumor cell death. Its molecular weight is 145.86 kDa.
Regn5678
Regn5678
😃Good
Catalog No. T9901A-793Alias Regn5678 (Anti-CD28 & PSMA), Regn5678, NezastomigCas No. 2657613-60-8
REGN5678 is a bispecific antibody that targets both PSMA on prostate cancer cells and CD28 on T cells, enhancing immune activation. This drug is being developed to treat prostate cancer by redirecting T cells to tumors expressing PSMA, thereby promoting tumor cell death. Its molecular weight is 145.86 kDa.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Chemical Properties
| Description | REGN5678 is a bispecific antibody that targets both PSMA on prostate cancer cells and CD28 on T cells, enhancing immune activation. This drug is being developed to treat prostate cancer by redirecting T cells to tumors expressing PSMA, thereby promoting tumor cell death. Its molecular weight is 145.86 kDa. |
| Synonyms | Regn5678 (Anti-CD28 & PSMA), Regn5678, Nezastomig |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Cas No. | 2657613-60-8 |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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