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Phomoxanthone A
🥰Excellent
Catalog No. TN11212Cas No. 359844-69-2
Phomoxanthone A is a flavonoid dimer isolated from Phomopsis. It exhibits antimalarial activity against the resistant strain of Plasmodium falciparum (K1, IC50 = 0.11 µg/mL) and displays antitubercular properties against Mycobacterium tuberculosis (H37Ra strain, MIC = 0.50 µg/mL). Additionally, Phomoxanthone A shows cytotoxicity in KB, BC-1, and Vero cells with IC50 values of 0.99, 0.51, and 1.4 µg/mL, respectively.
Phomoxanthone A
🥰Excellent
Catalog No. TN11212Cas No. 359844-69-2
Phomoxanthone A is a flavonoid dimer isolated from Phomopsis. It exhibits antimalarial activity against the resistant strain of Plasmodium falciparum (K1, IC50 = 0.11 µg/mL) and displays antitubercular properties against Mycobacterium tuberculosis (H37Ra strain, MIC = 0.50 µg/mL). Additionally, Phomoxanthone A shows cytotoxicity in KB, BC-1, and Vero cells with IC50 values of 0.99, 0.51, and 1.4 µg/mL, respectively.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Phomoxanthone A is a flavonoid dimer isolated from Phomopsis. It exhibits antimalarial activity against the resistant strain of Plasmodium falciparum (K1, IC50 = 0.11 µg/mL) and displays antitubercular properties against Mycobacterium tuberculosis (H37Ra strain, MIC = 0.50 µg/mL). Additionally, Phomoxanthone A shows cytotoxicity in KB, BC-1, and Vero cells with IC50 values of 0.99, 0.51, and 1.4 µg/mL, respectively. |
| Molecular Weight | 750.70 |
| Formula | C38H38O16 |
| Cas No. | 359844-69-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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