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Cergutuzumab
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Catalog No. T9901A-763 Copy Product Info
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Cergutuzumab (RG7813) is a tumor-targeted immunocytokine comprising a humanized anti-CEA monoclonal antibody fused to an engineered interleukin-2 variant (IL-2v). By specifically binding to Carcinoembryonic Antigen (CEA) on tumor cells, Cergutuzumab delivers IL-2v directly to the tumor microenvironment. This selectively activates cytotoxic CD8+ T cells and NK cells while minimizing the systemic toxicity typically associated with wild-type IL-2 therapy.
Cas No. 1622305-37-6
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $223 | 4-6 weeks | 4-6 weeks | |
| 5 mg | $672 | 4-6 weeks | 4-6 weeks | |
| 10 mg | $1,070 | 4-6 weeks | 4-6 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Cergutuzumab (RG7813) is a tumor-targeted immunocytokine comprising a humanized anti-CEA monoclonal antibody fused to an engineered interleukin-2 variant (IL-2v). By specifically binding to Carcinoembryonic Antigen (CEA) on tumor cells, Cergutuzumab delivers IL-2v directly to the tumor microenvironment. This selectively activates cytotoxic CD8+ T cells and NK cells while minimizing the systemic toxicity typically associated with wild-type IL-2 therapy. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CEACAM5/CEA/CD66e |
| Cas No. | 1622305-37-6 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Cergutuzumab chemical structure
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