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Teclistamab
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Catalog No. T76881Cas No. 2119595-80-9
Alias JNJ-64007957, JNJ64007957
Teclistamab (JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor expressed on the surface of t-cells and the b-cell maturation antigen (BCMA) expressed on the surface of malignant multiple myeloma b-lineage cells for the treatment of relapsed and refractory multiple myeloma.
Teclistamab
Teclistamab
😃Good
Purity: 95%
Catalog No. T76881Alias JNJ-64007957, JNJ64007957Cas No. 2119595-80-9
Teclistamab (JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor expressed on the surface of t-cells and the b-cell maturation antigen (BCMA) expressed on the surface of malignant multiple myeloma b-lineage cells for the treatment of relapsed and refractory multiple myeloma.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $689 | - | In Stock | |
| 5 mg | $1,590 | - | In Stock | |
| 10 mg | $2,180 | - | In Stock | |
| 25 mg | $3,230 | - | In Stock | |
| 50 mg | $4,370 | 8-10 weeks | 8-10 weeks | |
| 100 mg | $5,890 | 8-10 weeks | 8-10 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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| Description | Teclistamab (JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor expressed on the surface of t-cells and the b-cell maturation antigen (BCMA) expressed on the surface of malignant multiple myeloma b-lineage cells for the treatment of relapsed and refractory multiple myeloma. |
| In vitro | Methods: Frozen BM MNCs were treated with Teclistamab (0-532 nM) with or without exogenous healthy T cells to measure target engagement and killing. Results: Teclistamab-induced cytotoxicity in BM MNCs had comparable EC50s (1.5-4.2 nM) in all 3 patient samples; Teclistamab-mediated T cell activation was also similar in all BM MNC samples with EC50s (0.93 - 1.75 nM). [1] |
| Synonyms | JNJ-64007957, JNJ64007957 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF17/BCMA/CD269 & CD3 |
| Molecular Weight | 143.64 kDa |
| Cas No. | 2119595-80-9 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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