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Cibisatamab
Catalog No. T76674 Copy Product Info
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Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer.
Cibisatamab
Copy Product Info🥰Excellent
Catalog No. T76674
Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer.
Cas No. 1855925-27-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $562 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,650 | - | In Stock | |
| 25 mg | $2,460 | - | In Stock | |
| 50 mg | $3,320 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer. |
| Reactivity | Human |
| Verified Activity | 1. Immobilized Human CD3e Protein (His) (TMPY-01191) at 1 μg/mL (100 μL/well) can bind Cibisatamab. The EC50 is 19.880 ng/mL. 2. Immobilized Human CEACAM5 Protein (His) (TMPY-01647) at 1 μg/mL (100 μL/well) can bind Cibisatamab. The EC50 is 6.147 ng/mL.   |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD3E & CEACAM5 |
| Molecular Weight | 191.1 kDa |
| Cas No. | 1855925-27-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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