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Cibisatamab
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Catalog No. T76674Cas No. 1855925-27-7
Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer.
Cibisatamab
Copy Product Info😃Good
Catalog No. T76674Cas No. 1855925-27-7
Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $562 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,650 | - | In Stock | |
| 25 mg | $2,460 | - | In Stock | |
| 50 mg | $3,320 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:> 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer. |
| Reactivity | Human |
| Verified Activity | 1. Immobilized Human CD3e Protein (His) (TMPY-01191) at 1 μg/mL (100 μL/well) can bind Cibisatamab. The EC50 is 19.880 ng/mL. 2. Immobilized Human CEACAM5 Protein (His) (TMPY-01647) at 1 μg/mL (100 μL/well) can bind Cibisatamab. The EC50 is 6.147 ng/mL.   |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD3E & CEACAM5 |
| Molecular Weight | 191.1 kDa |
| Cas No. | 1855925-27-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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