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Ammocidin
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Catalog No. TN9146Cas No. 376590-20-4
Ammocidin is an apoptosis inducer in Ras-dependent cells. It triggers apoptosis in Ras-dependent Ba/F3-V12 cells with an IC50 of 66 ng/mL. Additionally, Ammocidin significantly reduces the phosphorylation levels of MAPK and S6K, which mediate the anti-apoptotic functions of Ras.
Ammocidin
Ammocidin
😃Good
Catalog No. TN9146Cas No. 376590-20-4
Ammocidin is an apoptosis inducer in Ras-dependent cells. It triggers apoptosis in Ras-dependent Ba/F3-V12 cells with an IC50 of 66 ng/mL. Additionally, Ammocidin significantly reduces the phosphorylation levels of MAPK and S6K, which mediate the anti-apoptotic functions of Ras.
| Pack Size | Price | Availability | Quantity |
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| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ammocidin is an apoptosis inducer in Ras-dependent cells. It triggers apoptosis in Ras-dependent Ba/F3-V12 cells with an IC50 of 66 ng/mL. Additionally, Ammocidin significantly reduces the phosphorylation levels of MAPK and S6K, which mediate the anti-apoptotic functions of Ras. |
| Molecular Weight | 1157.38 |
| Formula | C59H96O22 |
| Cas No. | 376590-20-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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