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Arcyriaflavin A

Name: Arcyriaflavin A
Brand: TargetMol
SKU: T21858
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21858Cas No. 118458-54-1

Arcyriaflavin A is derived from Eudistoma sp. It inhibits D1-CDK4, B-CDK1 and CaMKII with IC50 values of 0.14μM, 1.13μM and 0.025μM, respectively. Arcyriaflavin A also inhibits HCT-116 and NCI-H460 cells with IC50 values of 0.85μM and 0.59μM, respectively.

Arcyriaflavin A

🥰Excellent

Purity: 99.64%

Catalog No. T21858Cas No. 118458-54-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$113	In Stock	In Stock
10 mg	$181	In Stock	In Stock
25 mg	$322	In Stock	In Stock
50 mg	$500	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.64%

Appearance:Solid

Color:Red

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Arcyriaflavin A is derived from Eudistoma sp. It inhibits D1-CDK4, B-CDK1 and CaMKII with IC50 values of 0.14μM, 1.13μM and 0.025μM, respectively. Arcyriaflavin A also inhibits HCT-116 and NCI-H460 cells with IC50 values of 0.85μM and 0.59μM, respectively.
In vitro	Arcyriaflavin A has inhibitory effects on D1-CDK4, B-CDK1 and CaMKII, with IC50 values of 0.14μM, 1.13μM and 0.025μM, respectively. Arcyriaflavin A has inhibitory effects on HCT-116 and NCI-H460 cells, with IC50 values of 0.85μM and 0.59μM, respectively.

Chemical Properties

Molecular Weight	325.32
Formula	C₂₀H₁₁N₃O₂
Cas No.	118458-54-1
Smiles	O=C1NC(=O)C2=C1C1=C(NC3=C1C=CC=C3)C1=C2C2=C(N1)C=CC=C2
Relative Density.	1.621 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (61.48 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0739 mL	15.3695 mL	30.7390 mL	153.6948 mL
5 mM	0.6148 mL	3.0739 mL	6.1478 mL	30.7390 mL
10 mM	0.3074 mL	1.5369 mL	3.0739 mL	15.3695 mL
20 mM	0.1537 mL	0.7685 mL	1.5369 mL	7.6847 mL
50 mM	0.0615 mL	0.3074 mL	0.6148 mL	3.0739 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc