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(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid

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Catalog No. T36562Cas No. 339534-01-9

(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid elicits concentration-dependent contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of hormone-independent prostate carcinoma PC-3 cells.

(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid

(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid

😃Good
Catalog No. T36562Cas No. 339534-01-9
(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid elicits concentration-dependent contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of hormone-independent prostate carcinoma PC-3 cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
250 μg$17835 days35 days
500 μg$33335 days35 days
1 mg$62335 days35 days
5 mg$2,73035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
(5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid elicits concentration-dependent contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of hormone-independent prostate carcinoma PC-3 cells.
Chemical Properties
Molecular Weight320.473
FormulaC20H32O3
Cas No.339534-01-9
SmilesCCCCC[C@@H](O)C#C\C=C/CCCC\C=C/CCCC(O)=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 20 mg/mL (62.41 mM), Sonication is recommended.
DMSO: 20 mg/mL (62.41 mM), Sonication is recommended.
Ethanol: Miscible
Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL (1.56 mM), Sonication is recommended.
Solution Preparation Table
DMF/DMSO
1mg5mg10mg50mg
5 mM0.6241 mL3.1204 mL6.2408 mL31.2039 mL
10 mM0.3120 mL1.5602 mL3.1204 mL15.6019 mL
20 mM0.1560 mL0.7801 mL1.5602 mL7.8010 mL
50 mM0.0624 mL0.3120 mL0.6241 mL3.1204 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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