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Synonyms: KK-LC-1, KKLC1, CXorf61, CT83


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $286 | 7-10 days | 7-10 days | |
| 20 µg | $448 | 7-10 days | 7-10 days | |
| 50 µg | $829 | 7-10 days | 7-10 days | |
| 100 µg | $1,320 | 7-10 days | 7-10 days | |
| 200 µg | $2,090 | 7-10 days | 7-10 days | |
| 500 µg | $3,920 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein, Human, MHC (His & Avi) is expressed in HEK293 Cells. The accession number is A0A140T913(HLA-A*02:01)&P61769(B2M)&ILNNFPHSI. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | A0A140T913(HLA-A*02:01)&P61769(B2M)&ILNNFPHSI |
| Construction | Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and ILNNFPHSI peptide |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | KK-LC-1, KKLC1, CXorf61, CT83 |
| Research Background | Kita-Kyushu lung cancer antigen-1 (KK-LC-1), encoded by CT83, includes epitope peptides recognized by cytotoxic T lymphocytes (CTLs). CTLs against KK-LC-1 predominantly accumulate among tumor-infiltrating lymphocytes, which leads to a good response to adaptive immunotherapy. Except for the testis, KK-LC-1 is not expressed in normal tissues. It is expressed in 33%, 82%, and 75% of non-small cell lung cancers, GC, and triple-negative breast cancers, respectively. |
| Molecular Weight | 258 kDa (Predicted); 260-265 kDa (Non-reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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