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Anti-LILRB3 Antibody (2Q980)

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Catalog No. TMAY-03449

Anti-LILRB3 Antibody (2Q980) is a Rabbit antibody targeting LILRB3. Anti-LILRB3 Antibody (2Q980) can be used in ELISA.

Anti-LILRB3 Antibody (2Q980)

Anti-LILRB3 Antibody (2Q980)

😃Good
Catalog No. TMAY-03449
Anti-LILRB3 Antibody (2Q980) is a Rabbit antibody targeting LILRB3. Anti-LILRB3 Antibody (2Q980) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-LILRB3 Antibody (2Q980) is a Rabbit antibody targeting LILRB3. Anti-LILRB3 Antibody (2Q980) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
2Q980
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse LILRB3 (TMPY-02633; AAC53219.1; Met1-Tyr640).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLeukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein that belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in the modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse LILRB3 protein (TMPY-02633)
Antigen Species
Mouse
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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