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IA65
(Synonyms: Orai1 Agonist, IA-65, IA 65) Copy Product Info
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Synonyms: Orai1 Agonist, IA-65, IA 65
Catalog No. T202304 Copy Product Info
Purity: 99.70%
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IA65 is a selective small molecule agonist that enhances Orai1 channel-mediated calcium influx and activates calcium-dependent inactivation mechanisms. IA65 serves as an ideal tool for studying intracellular calcium homeostasis and is also used to investigate the migratory behavior of vascular smooth muscle cells, skeletal muscle function, and immune system.
Cas No. 255833-41-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $691 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.70%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | IA65 is a selective small molecule agonist that enhances Orai1 channel-mediated calcium influx and activates calcium-dependent inactivation mechanisms. IA65 serves as an ideal tool for studying intracellular calcium homeostasis and is also used to investigate the migratory behavior of vascular smooth muscle cells, skeletal muscle function, and immune system. |
| Synonyms | Orai1 Agonist, IA-65, IA 65 |
| Molecular Weight | 364.34 |
| Formula | C17H11F3N2O2S |
| Cas No. | 255833-41-1 |
| Smiles | O=C(O)C1=CC=C(C=C1)NC2=NC(=C(S2)C=3C=CC=CC3)C(F)(F)F |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Related Tags: IA65 chemical structure | IA65 formula | IA65 molecular weight
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