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2,5-Deoxyfructosazine (hydrochloride)

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Catalog No. T37276Cas No. 17460-13-8

2,5-Deoxyfructosazine is a pyrazine derivative found in cured tobacco and used as a flavoring agent in the food and tobacco industry. It can be produced via pyrolytic decomposition of natural compounds or through the reaction of sugars with alcoholic ammonia. Additionally, it forms from the breakdown of D-glucosamine at neutral pH. Similar to glucosamine, 2,5-deoxyfructosazine exhibits DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).

2,5-Deoxyfructosazine (hydrochloride)

2,5-Deoxyfructosazine (hydrochloride)

😃Good
Catalog No. T37276Cas No. 17460-13-8
2,5-Deoxyfructosazine is a pyrazine derivative found in cured tobacco and used as a flavoring agent in the food and tobacco industry. It can be produced via pyrolytic decomposition of natural compounds or through the reaction of sugars with alcoholic ammonia. Additionally, it forms from the breakdown of D-glucosamine at neutral pH. Similar to glucosamine, 2,5-deoxyfructosazine exhibits DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$12935 days35 days
5 mg$24835 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
2,5-Deoxyfructosazine is a pyrazine derivative found in cured tobacco and used as a flavoring agent in the food and tobacco industry. It can be produced via pyrolytic decomposition of natural compounds or through the reaction of sugars with alcoholic ammonia. Additionally, it forms from the breakdown of D-glucosamine at neutral pH. Similar to glucosamine, 2,5-deoxyfructosazine exhibits DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).
Chemical Properties
Molecular Weight304.3
FormulaC12H20N2O7
Cas No.17460-13-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.07 mg/mL (10.09 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (32.86 mM), Sonication is recommended.
Solution Preparation Table
DMSO/PBS (pH 7.2)
1mg5mg10mg50mg
1 mM3.2862 mL16.4312 mL32.8623 mL164.3115 mL
5 mM0.6572 mL3.2862 mL6.5725 mL32.8623 mL
10 mM0.3286 mL1.6431 mL3.2862 mL16.4312 mL
PBS (pH 7.2)
1mg5mg10mg50mg
20 mM0.1643 mL0.8216 mL1.6431 mL8.2156 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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