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Antibacterial agent 132

🥰Excellent
Catalog No. T72310Cas No. 3026790-18-8

Antibacterial agent 132 showed antimicrobial activity against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibited aromatase enzyme with IC50 of 0.047 μM.

Antibacterial agent 132

Antibacterial agent 132

🥰Excellent
Purity: 98%
Catalog No. T72310Cas No. 3026790-18-8
Antibacterial agent 132 showed antimicrobial activity against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibited aromatase enzyme with IC50 of 0.047 μM.
Pack SizePriceAvailabilityQuantity
1 mg$82In Stock
5 mg$195In Stock
10 mg$285In Stock
25 mg$449In Stock
50 mg$601In Stock
100 mg$805In Stock
200 mg$1,090In Stock
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Batch Information

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Purity:98%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Antibacterial agent 132 showed antimicrobial activity against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibited aromatase enzyme with IC50 of 0.047 μM.
Targets&IC50
NIH3T3 cells:10 μM
In vitro
Having cytotoxicity against the NIH/3T3 healthy cell line with an IC50 of 10 μM, Antibacterial agent 132 (compound 4j)[1].
Chemical Properties
Molecular Weight444.94
FormulaC24H17ClN4OS
Cas No.3026790-18-8
SmilesClC=1N=C2C=CC(OC)=CC2=CC1C=NNC3=NC(=CS3)C=4C=CC=C5C=CC=CC54
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (123.61 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2475 mL11.2375 mL22.4749 mL112.3747 mL
5 mM0.4495 mL2.2475 mL4.4950 mL22.4749 mL
10 mM0.2247 mL1.1237 mL2.2475 mL11.2375 mL
20 mM0.1124 mL0.5619 mL1.1237 mL5.6187 mL
50 mM0.0449 mL0.2247 mL0.4495 mL2.2475 mL
100 mM0.0225 mL0.1124 mL0.2247 mL1.1237 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Fungal
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