Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer). Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | NU1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer). Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h. |
Molecular Weight | 253.26 |
Formula | C14H11N3O2 |
CAS No. | 188106-83-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NU1085 188106-83-4 CDK8IN-18 NU 1085 ZINC 584617986 CDK8 IN 18 NU-1085 ZINC-584617986 CDK8-IN-18 CDK8IN18 CDK8-IN18 CDK8 IN18 CDK8 IN-18 inhibitor inhibit