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dCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $70 | In Stock | |
10 mg | $92 | In Stock | |
25 mg | $169 | In Stock | |
50 mg | $282 | In Stock | |
100 mg | $453 | In Stock | |
200 mg | $649 | In Stock |
Description | dCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells. |
In vitro | dCeMM1 (0-100 µM; 3 days) inhibited cell growth with EC50 values of 3 and 8 µ M for WT and UBE2Mmut KBM7 cells, respectively, and at 10 µ M for 12-16 hours, it reduced RBM39 expression in WT KBM7 cells [1]. |
Molecular Weight | 369.23 |
Formula | C14H13BrN2O3S |
Cas No. | 118719-16-7 |
Smiles | Cc1ccc(cc1)S(=O)(=O)NN=Cc1cc(Br)ccc1O |
Relative Density. | no data available |
Color | White |
Appearance | Solid |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
Solubility Information | DMSO: 1.8 mg/mL (4.88 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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