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SjDX5-53

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Catalog No. TP3709Cas No. 2767993-73-5

SjDX5-53 is a selective TLR2 inducer derived from a 3 kDa peptide found in Schistosoma japonicum eggs. This compound supports the production and inhibitory function of regulatory T cells (Tregs) by inducing tolerogenic dendritic cells (tolDCs), thereby suppressing inflammatory Th1 and Th17 responses. SjDX5-53 is primarily studied for its therapeutic potential in autoimmune and inflammatory conditions, such as colitis and psoriasis.

SjDX5-53

SjDX5-53

😃Good
Catalog No. TP3709Cas No. 2767993-73-5
SjDX5-53 is a selective TLR2 inducer derived from a 3 kDa peptide found in Schistosoma japonicum eggs. This compound supports the production and inhibitory function of regulatory T cells (Tregs) by inducing tolerogenic dendritic cells (tolDCs), thereby suppressing inflammatory Th1 and Th17 responses. SjDX5-53 is primarily studied for its therapeutic potential in autoimmune and inflammatory conditions, such as colitis and psoriasis.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
SjDX5-53 is a selective TLR2 inducer derived from a 3 kDa peptide found in Schistosoma japonicum eggs. This compound supports the production and inhibitory function of regulatory T cells (Tregs) by inducing tolerogenic dendritic cells (tolDCs), thereby suppressing inflammatory Th1 and Th17 responses. SjDX5-53 is primarily studied for its therapeutic potential in autoimmune and inflammatory conditions, such as colitis and psoriasis.
Chemical Properties
Molecular Weight3223.50
FormulaC128H208N46O46S3
Cas No.2767993-73-5
SmilesC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CCC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCSC)=O)CCC(N)=O)=O)CC(N)=O)=O)[C@@H](C)O)=O)C)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CO)=O)CCC2)CCC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC1
SequenceGly-Gln-Met-Gln-Gln-Gln-Gln-Arg-Pro-Gln-Gln-Met-Gln-Pro-Ser-Gln-Gln-Tyr-Ala-Thr-Asn-Gln-Met-Thr-Asn-Ser-
Sequence ShortGQMQQQQRPQQMQPSQQYATNQMTNSR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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