store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TREM2 agonist-2 (I-192) is an orally active and potent myeloid triggered receptor 2 (TREM2) agonist for the study of neurodegenerative diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 283.00 | |
5 mg | In stock | $ 698.00 | |
10 mg | In stock | $ 1,160.00 | |
25 mg | In stock | $ 2,130.00 | |
50 mg | In stock | $ 2,780.00 | |
100 mg | In stock | $ 3,520.00 |
Description | TREM2 agonist-2 (I-192) is an orally active and potent myeloid triggered receptor 2 (TREM2) agonist for the study of neurodegenerative diseases. |
In vitro | Treatment with TREM2 agonist-2 (0-100μM; 16 hours) activated hTREM2 in HEK293 cells, with an EC50 value less than 0.05μM for cell viability assay[1]. |
In vivo | The results indicate that TREM2 agonist-2 (50 mg/kg; twice daily; oral gavage for one day) can bind to the TREM2 target, which can interact with microglial cells[1]. |
Molecular Weight | 451.92 |
Formula | C24H23ClFN5O |
CAS No. | 2738485-98-6 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.19 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TREM2 agonist-2 2738485-98-6 Others inhibitor inhibit