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Anti-Mouse CD40 Antibody (FGK4.5/FGK45)
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Catalog No. T9901A-561 Copy Product Info
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Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a monoclonal antibody against mouse CD40 that specifically binds to the CD40 molecule and activates B cells and antigen-presenting cells. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhances T cell responses, dendritic cell maturation, and NK cell activation. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) can be used in research related to cancer, infection, inflammation, and immunology.
Anti-Mouse CD40 Antibody
(FGK4.5/FGK45)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $397 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $1,530 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:≥95% Determined by SDS-PAGE
Appearance:Liquid
Color:Transparent
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| Description | Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a monoclonal antibody against mouse CD40 that specifically binds to the CD40 molecule and activates B cells and antigen-presenting cells. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhances T cell responses, dendritic cell maturation, and NK cell activation. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) can be used in research related to cancer, infection, inflammation, and immunology. |
| In vivo | Methods: C57BL/6 mice were administered 200 μg of Anti-Mouse CD40 Antibody (FGK4.5/FGK45) intraperitoneally on Day 0, followed by 100 μg on Days 3, 7, and 10. The mice were euthanized after the final injection. Results: Anti-Mouse CD40 Antibody (FGK4.5/FGK45) induces the expression of IL-15Rα in C57BL/6 mice. [1] Methods: To investigate the antitumor efficacy of Anti-Mouse CD40 Antibody (FGK4.5/FGK45), mice in the CT26/MC38 tumor model were administered 200 μg intraperitoneally on Day 0, followed by 100 μg intraperitoneal injections of Anti-Mouse CD40 Antibody (FGK4.5/FGK45) on Days 3, 7, and 10, respectively. Results: Anti-Mouse CD40 Antibody (FGK4.5/FGK45) inhibited tumor growth and prolonged the survival of the mice.[1] Methods: To investigate the effects of Anti-Mouse CD40 Antibody (FGK4.5/FGK45) on dendritic cells, a mouse model of vesicular stomatitis virus (VSV) infection was established. One day after infection, Anti-Mouse CD40 Antibody (FGK4.5/FGK45) (100 μg) was administered via intraperitoneal injection. Results: Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhanced CD8+ T cell responses and dendritic cell maturation in the mouse model. [2] Methods: Anti-Mouse CD40 Antibody (FGK4.5/FGK45) (100 μg) was administered intravenously on days 0 and 1 post-surgery in a mouse model of vascularized heart transplantation. Results: Anti-Mouse CD40 Antibody (FGK4.5/FGK45) promotes the accumulation of immunogenic macrophages and prevents the induction of tolerance in mice with a vascularized heart transplant model. [3] |
| Clone | FGK4.5/FGK45 |
| Reactivity | Mouse |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | CD40 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-Mouse CD40 Antibody (FGK4.5/FGK45) in vivo
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