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MB-311
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Catalog No. T9901A-1267 Copy Product Info
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MB-311 is a fully humanized monoclonal antibody targeting the tumor-associated antigen Lewis Y (LeY), acting by specifically binding to the LeY carbohydrate structures on the surface of tumor cells. The compound is an essential tool for investigating immunotherapy mechanisms against carbohydrate antigens, aiming to achieve precise clearance of tumor cells by inducing robust antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Antibody Information
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| Description | MB-311 is a fully humanized monoclonal antibody targeting the tumor-associated antigen Lewis Y (LeY), acting by specifically binding to the LeY carbohydrate structures on the surface of tumor cells. The compound is an essential tool for investigating immunotherapy mechanisms against carbohydrate antigens, aiming to achieve precise clearance of tumor cells by inducing robust antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). |
| In vitro | In human Lewis Y-expressing tumor cell lines, MB-311 induced potent ADCC and stimulated the release of TNF-alpha and IFN-gamma [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | Lewis Y |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: MB-311 chemical structure | MB-311 in vitro
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