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19-Oxocinobufotalin

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Catalog No. TN1200Cas No. 24512-60-5

19-Oxocinobufotalin is a natural product that inhibits epithelial-mesenchymal transition (EMT) and attenuates growth, migration, and invasion in PC3 cells.

19-Oxocinobufotalin

19-Oxocinobufotalin

😃Good
Purity: 99.99%
Catalog No. TN1200Cas No. 24512-60-5
19-Oxocinobufotalin is a natural product that inhibits epithelial-mesenchymal transition (EMT) and attenuates growth, migration, and invasion in PC3 cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$147-In Stock
5 mg$372-In Stock
10 mg$553-In Stock
25 mg$893-In Stock
50 mg$1,220-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.99%
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Product Introduction

Bioactivity
Description
19-Oxocinobufotalin is a natural product that inhibits epithelial-mesenchymal transition (EMT) and attenuates growth, migration, and invasion in PC3 cells.
In vitro
19-Oxocinobufotalin(50 nM) can inhibit the proliferation of PC3 cells by up to 10% [2].
Chemical Properties
Molecular Weight472.53
FormulaC26H32O8
Cas No.24512-60-5
SmilesC[C@]12[C@]3([C@](O3)([C@H](OC(C)=O)[C@@H]1C=4C=CC(=O)OC4)[H])[C@]5([C@](CC2)([C@]6(C=O)[C@](O)(CC5)C[C@@H](O)CC6)[H])[H]
Relative Density.1.40 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40.00 mg/mL (84.65 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1163 mL10.5813 mL21.1627 mL105.8134 mL
5 mM0.4233 mL2.1163 mL4.2325 mL21.1627 mL
10 mM0.2116 mL1.0581 mL2.1163 mL10.5813 mL
20 mM0.1058 mL0.5291 mL1.0581 mL5.2907 mL
50 mM0.0423 mL0.2116 mL0.4233 mL2.1163 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

19-Oxocinobufotalin19Oxocinobufotalin19 Oxocinobufotalin
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