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NSC 48160

🥰Excellent
Catalog No. T79783Cas No. 6640-90-0
Alias NSC48160

NSC 48160 is a small molecule compound with anti-pancreatic cancer activity that inhibits the growth of pancreatic cancer cells, induces apoptosis of pancreatic cancer cells through the mitochondrial pathway and inhibits metastasis of two types of pancreatic cancer cells in vitro, and can freeze the intermediate of Ras-GTP hydrolysis in the open non-signaling conformation with high affinity and high specificity in silico.

NSC 48160

NSC 48160

🥰Excellent
Purity: 98.10%
Catalog No. T79783Alias NSC48160Cas No. 6640-90-0
NSC 48160 is a small molecule compound with anti-pancreatic cancer activity that inhibits the growth of pancreatic cancer cells, induces apoptosis of pancreatic cancer cells through the mitochondrial pathway and inhibits metastasis of two types of pancreatic cancer cells in vitro, and can freeze the intermediate of Ras-GTP hydrolysis in the open non-signaling conformation with high affinity and high specificity in silico.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$74-In Stock
5 mg$179-In Stock
10 mg$289-In Stock
25 mg$579-In Stock
50 mg$953-In Stock
100 mg$1,530-In Stock
1 mL x 10 mM (in DMSO)$198-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.10%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
NSC 48160 is a small molecule compound with anti-pancreatic cancer activity that inhibits the growth of pancreatic cancer cells, induces apoptosis of pancreatic cancer cells through the mitochondrial pathway and inhibits metastasis of two types of pancreatic cancer cells in vitro, and can freeze the intermediate of Ras-GTP hydrolysis in the open non-signaling conformation with high affinity and high specificity in silico.
SynonymsNSC48160
Chemical Properties
Molecular Weight275.43
FormulaC18H29NO
Cas No.6640-90-0
SmilesCc1cc(cc(CNC2CCCCC2)c1O)C(C)(C)C
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (290.45 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.98 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6307 mL18.1534 mL36.3069 mL181.5343 mL
5 mM0.7261 mL3.6307 mL7.2614 mL36.3069 mL
10 mM0.3631 mL1.8153 mL3.6307 mL18.1534 mL
20 mM0.1815 mL0.9077 mL1.8153 mL9.0767 mL
50 mM0.0726 mL0.3631 mL0.7261 mL3.6307 mL
100 mM0.0363 mL0.1815 mL0.3631 mL1.8153 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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