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Glutathione ethyl ester acetate
🥰Excellent
Catalog No. T78616L1
Alias Glutathione ethyl ester acetate（92614-59-0 Free base）
Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells.
Glutathione ethyl ester acetate
🥰Excellent
Purity: 97.49%
Catalog No. T78616L1Alias Glutathione ethyl ester acetate（92614-59-0 Free base）
Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $38 | In Stock | |
| 5 mg | $84 | In Stock | |
| 10 mg | $126 | In Stock | |
| 25 mg | $227 | In Stock | |
| 50 mg | $340 | In Stock | |
| 100 mg | $510 | In Stock |
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Purity:97.49%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells. |
| In vitro | Methods: Glutathione ethyl ester acetate (5 mM) was used to treat aged dairy cow oocytes. The effects of cell-permeable glutathione (GSH) donor Glutathione ethyl ester acetate (GSH-OEt) on the developmental capacity of aged dairy cow oocytes were studied. Results: Glutathione ethyl ester acetate can reduce the content of intracellular reactive oxygen species (ROS), promote meiotic progression, increase the proportion of oocytes with mature cytoplasm (cortical granules evenly dispersed), and improve the normal fertilization rate, blastocyst development rate and diploid blastocyst ratio. [1] |
| In vivo | Methods: Glutathione ethyl ester acetate (6 mmol/kg, intraperitoneal injection) was used to treat mice starved for 24 hours, and their internal metabolism was analyzed. Results: Glutathione ethyl ester acetate can improve the swimming endurance of mice and reduce exercise-induced muscle lipid peroxidation, but it has certain metabolic and oxidative stress side effects on the kidneys. [2] |
| Alias | Glutathione ethyl ester acetate（92614-59-0 Free base） |
| Molecular Weight | 395.43 |
| Formula | C14H25N3O8S |
| Smiles | CCOC(CNC([C@H](CS)NC(CC[C@H](N)C(O)=O)=O)=O)=O.CC(O)=O |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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