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Glutathione ethyl ester acetate
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Catalog No. T78616L1
Alias Glutathione ethyl ester acetate（92614-59-0 Free base）
Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells.
Glutathione ethyl ester acetate
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Purity: 97.49%
Catalog No. T78616L1Alias Glutathione ethyl ester acetate（92614-59-0 Free base）
Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $38 | - | In Stock | |
| 5 mg | $84 | - | In Stock | |
| 10 mg | $126 | - | In Stock | |
| 25 mg | $227 | - | In Stock | |
| 50 mg | $340 | - | In Stock | |
| 100 mg | $510 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.49%
Appearance:Solid
Color:White
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells. |
| In vitro | Methods: Glutathione ethyl ester acetate (5 mM) was used to treat aged dairy cow oocytes. The effects of cell-permeable glutathione (GSH) donor Glutathione ethyl ester acetate (GSH-OEt) on the developmental capacity of aged dairy cow oocytes were studied. Results: Glutathione ethyl ester acetate can reduce the content of intracellular reactive oxygen species (ROS), promote meiotic progression, increase the proportion of oocytes with mature cytoplasm (cortical granules evenly dispersed), and improve the normal fertilization rate, blastocyst development rate and diploid blastocyst ratio. [1] |
| In vivo | Methods: Glutathione ethyl ester acetate (6 mmol/kg, intraperitoneal injection) was used to treat mice starved for 24 hours, and their internal metabolism was analyzed. Results: Glutathione ethyl ester acetate can improve the swimming endurance of mice and reduce exercise-induced muscle lipid peroxidation, but it has certain metabolic and oxidative stress side effects on the kidneys. [2] |
| Synonyms | Glutathione ethyl ester acetate（92614-59-0 Free base） |
| Molecular Weight | 395.43 |
| Formula | C14H25N3O8S |
| Smiles | CCOC(CNC([C@H](CS)NC(CC[C@H](N)C(O)=O)=O)=O)=O.CC(O)=O |
| Sequence | H-gGlu-Cys-Gly-OEt |
| Sequence Short | XCG |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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