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ERRα antagonist-2

Name: ERRα antagonist-2
Brand: TargetMol
SKU: T61923
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T61923Cas No. 3032965-02-6

ERRα antagonist-2 (Compound 11) is an estrogen-related receptor α inverse agonist with an IC50 of 0.80 μM, capable of inhibiting migration and invasion in ER-negative MDA-MB-231 cells and suppressing breast cancer growth.

ERRα antagonist-2

🥰Excellent

Purity: 99.26%

Catalog No. T61923Cas No. 3032965-02-6

Pack Size	Price	Availability
1 mg	$37	In Stock
5 mg	$86	In Stock
10 mg	$139	In Stock
25 mg	$283	In Stock
50 mg	$455	In Stock
100 mg	$728	In Stock
200 mg	$982	In Stock

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Batch Information

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Purity:99.26%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	ERRα antagonist-2 (Compound 11) is an estrogen-related receptor α inverse agonist with an IC50 of 0.80 μM, capable of inhibiting migration and invasion in ER-negative MDA-MB-231 cells and suppressing breast cancer growth.
Targets&IC50	ERRα:0.80 μM

Chemical Properties

Molecular Weight	400.41
Formula	C₁₉H₁₆N₂O₆S
Cas No.	3032965-02-6
Smiles	O=S(C(C=C1)=CC=C1[N+]([O-])=O)(NC2=C(OC3=CC=C(C=C3)OC)C=CC=C2)=O
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (499.49 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4974 mL	12.4872 mL	24.9744 mL	124.8720 mL
5 mM	0.4995 mL	2.4974 mL	4.9949 mL	24.9744 mL
10 mM	0.2497 mL	1.2487 mL	2.4974 mL	12.4872 mL
20 mM	0.1249 mL	0.6244 mL	1.2487 mL	6.2436 mL
50 mM	0.0499 mL	0.2497 mL	0.4995 mL	2.4974 mL
100 mM	0.0250 mL	0.1249 mL	0.2497 mL	1.2487 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc