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Corynoxine hydrochloride(6877-32-3(free base))

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Catalog No. T5143

Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.

Corynoxine hydrochloride(6877-32-3(free base))
Other Forms of Corynoxine hydrochloride(6877-32-3(free base)):

Corynoxine hydrochloride(6877-32-3(free base))

😃Good
Purity: 99.72%
Catalog No. T5143
Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
Pack SizePriceAvailabilityQuantity
1 mg$64Backorder
2 mg$92Backorder
5 mg$128Backorder
10 mg$185Backorder
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Purity:99.72%
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Product Introduction

Bioactivity
Description
Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
Chemical Properties
Molecular Weight420.93
FormulaC22H29ClN2O4
SmilesCl.[H][C@@]12C[C@@H]([C@H](CC)CN1CC[C@@]21C(=O)Nc2ccccc12)C(=C/OC)\C(=O)OC
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (118.78 mM), Sonication is recommended.
Ethanol: 50 mg/mL (118.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.3757 mL11.8785 mL23.7569 mL118.7846 mL
5 mM0.4751 mL2.3757 mL4.7514 mL23.7569 mL
10 mM0.2376 mL1.1878 mL2.3757 mL11.8785 mL
20 mM0.1188 mL0.5939 mL1.1878 mL5.9392 mL
50 mM0.0475 mL0.2376 mL0.4751 mL2.3757 mL
100 mM0.0238 mL0.1188 mL0.2376 mL1.1878 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Corynoxine hydrochloride(6877-32-3(free base))Corynoxine hydrochloride(6877323(free base))Corynoxine hydrochloride(6877 32 3(free base))Autophagy
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