Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

SP94

😃Good
Catalog No. TP3858Cas No. 1158983-49-3

SP94 is a peptide ligand with high specificity for hepatocellular carcinoma cells. It selectively binds to various hepatocellular carcinoma cell lines in vitro. In mouse models of hepatocellular carcinoma, SP94 inhibits tumor growth by promoting tumor cell apoptosis (apoptosis) and reducing tumor angiogenesis. SP94 can serve as a specific probe for imaging hepatocellular carcinoma and is applicable in hepatocellular carcinoma research.

SP94

SP94

😃Good
Catalog No. TP3858Cas No. 1158983-49-3
SP94 is a peptide ligand with high specificity for hepatocellular carcinoma cells. It selectively binds to various hepatocellular carcinoma cell lines in vitro. In mouse models of hepatocellular carcinoma, SP94 inhibits tumor growth by promoting tumor cell apoptosis (apoptosis) and reducing tumor angiogenesis. SP94 can serve as a specific probe for imaging hepatocellular carcinoma and is applicable in hepatocellular carcinoma research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mgInquiryInquiryInquiry
50 mgInquiryInquiryInquiry
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
SP94 is a peptide ligand with high specificity for hepatocellular carcinoma cells. It selectively binds to various hepatocellular carcinoma cell lines in vitro. In mouse models of hepatocellular carcinoma, SP94 inhibits tumor growth by promoting tumor cell apoptosis (apoptosis) and reducing tumor angiogenesis. SP94 can serve as a specific probe for imaging hepatocellular carcinoma and is applicable in hepatocellular carcinoma research.
In vitro
SP94 (40 nM HspG41C-SM(PEG)n-SP94, 12/23 peptide/cage, 24 hours) selectively binds to HepG2 and Huh-7 cells, while showing no binding affinity to HeLa and RLN-8 cells.
In vivo
In the Mahlavu cell xenograft mouse model, SP94 (100 µg + PC94, single dose/1 mg/kg (SP94-LD), administered intravenously once or twice weekly for 2-4 consecutive weeks) inhibits the recovery of phage particles from tumor tissue, suppresses tumor growth by enhancing apoptosis in tumor cells, and reduces tumor angiogenesis.
Chemical Properties
Molecular Weight1337.60
FormulaC65H104N14O16
Cas No.1158983-49-3
SmilesC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@H](CO)N)=O)=O)CO)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)=O)[C@@H](C)O)=O)CCC1)[C@H](CC)C)=O)CC(C)C)(=O)N4[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCC4
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy SP94 | purchase SP94 | SP94 cost | order SP94 | SP94 chemical structure | SP94 in vivo | SP94 in vitro | SP94 formula | SP94 molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.