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Nrf2-Activator-12G
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Catalog No. T24546Cas No. 1554271-18-9
Alias Nrf2 Activator-IV, Nrf2 Activator IV
Nrf2-Activator-12G (compd 12g) is a direct activator of Nrf2 that induces robust expression of Nrf2-dependent antioxidant enzymes at both mRNA and protein levels in dopaminergic neuronal cells, thereby enhancing cellular defense against oxidative stress and providing a mechanistic platform for investigating neuroprotection and disease-modifying strategies in Parkinson’s disease research.
Nrf2-Activator-12G
😃Good
Purity: 99.92%
Catalog No. T24546Alias Nrf2 Activator-IV, Nrf2 Activator IVCas No. 1554271-18-9
Nrf2-Activator-12G (compd 12g) is a direct activator of Nrf2 that induces robust expression of Nrf2-dependent antioxidant enzymes at both mRNA and protein levels in dopaminergic neuronal cells, thereby enhancing cellular defense against oxidative stress and providing a mechanistic platform for investigating neuroprotection and disease-modifying strategies in Parkinson’s disease research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $30 | - | In Stock | |
| 5 mg | $64 | - | In Stock | |
| 10 mg | $106 | - | In Stock | |
| 25 mg | $176 | - | In Stock | |
| 50 mg | $262 | - | In Stock | |
| 100 mg | $389 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.92%
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Nrf2-Activator-12G (compd 12g) is a direct activator of Nrf2 that induces robust expression of Nrf2-dependent antioxidant enzymes at both mRNA and protein levels in dopaminergic neuronal cells, thereby enhancing cellular defense against oxidative stress and providing a mechanistic platform for investigating neuroprotection and disease-modifying strategies in Parkinson’s disease research. |
| In vivo | In mouse models of Parkinson’s disease, such as those induced by MPTP neurotoxicity, Nrf2-Activator-12G mitigate oxidative damage and reduce neuroinflammation [1]. |
| Synonyms | Nrf2 Activator-IV, Nrf2 Activator IV |
| Molecular Weight | 308.78 |
| Formula | C15H13ClO3S |
| Cas No. | 1554271-18-9 |
| Smiles | S(/C=C/C1=C(Cl)C=CC=C1)(=O)(=O)C2=C(OC)C=CC=C2 |
| Relative Density. | 1.308 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Storage | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (259.08 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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