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BND-35
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Catalog No. T9901A-1047 Copy Product Info
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BND-35 is a human monoclonal antibody (mAb) that targets LILRB4/ILT3/CD85k. It interferes with the interaction between ILT3 and APOE as well as fibronectin, thereby enhancing the pro-inflammatory activity of various myeloid cells and reversing T cell immunosuppression mediated by different inhibitory myeloid cells. BND-35 exhibits antitumor activity in hILT3 transgenic mouse tumor models.
BND-35
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Storage & Solubility Information
| Description | BND-35 is a human monoclonal antibody (mAb) that targets LILRB4/ILT3/CD85k. It interferes with the interaction between ILT3 and APOE as well as fibronectin, thereby enhancing the pro-inflammatory activity of various myeloid cells and reversing T cell immunosuppression mediated by different inhibitory myeloid cells. BND-35 exhibits antitumor activity in hILT3 transgenic mouse tumor models. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | LILRB4/IL-T3/CD85k |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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