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BND-35

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Catalog No. T9901A-1047

BND-35 is a human monoclonal antibody (mAb) that targets LILRB4/ILT3/CD85k. It interferes with the interaction between ILT3 and APOE as well as fibronectin, thereby enhancing the pro-inflammatory activity of various myeloid cells and reversing T cell immunosuppression mediated by different inhibitory myeloid cells. BND-35 exhibits antitumor activity in hILT3 transgenic mouse tumor models.

BND-35

BND-35

😃Good
Catalog No. T9901A-1047
BND-35 is a human monoclonal antibody (mAb) that targets LILRB4/ILT3/CD85k. It interferes with the interaction between ILT3 and APOE as well as fibronectin, thereby enhancing the pro-inflammatory activity of various myeloid cells and reversing T cell immunosuppression mediated by different inhibitory myeloid cells. BND-35 exhibits antitumor activity in hILT3 transgenic mouse tumor models.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
BND-35 is a human monoclonal antibody (mAb) that targets LILRB4/ILT3/CD85k. It interferes with the interaction between ILT3 and APOE as well as fibronectin, thereby enhancing the pro-inflammatory activity of various myeloid cells and reversing T cell immunosuppression mediated by different inhibitory myeloid cells. BND-35 exhibits antitumor activity in hILT3 transgenic mouse tumor models.
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin< 1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetLILRB4/IL-T3/CD85k
Chemical Properties
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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