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Valproic acid-d14 (sodium) is the deuterated form of Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) acts as an HDAC inhibitor, with an IC50 range of 0.5-2 mM, and inhibits the activity of HDAC1 (IC50, 400 μM) while also promoting the degradation of HDAC2. It activates the Notch1 signaling pathway and suppresses the proliferation of small cell lung cancer (SCLC) cells. Additionally, Valproic acid sodium salt is applicable in research related to epilepsy, bipolar disorder, and migraines.
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| Description | Valproic acid-d14 (sodium) is the deuterated form of Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) acts as an HDAC inhibitor, with an IC50 range of 0.5-2 mM, and inhibits the activity of HDAC1 (IC50, 400 μM) while also promoting the degradation of HDAC2. It activates the Notch1 signaling pathway and suppresses the proliferation of small cell lung cancer (SCLC) cells. Additionally, Valproic acid sodium salt is applicable in research related to epilepsy, bipolar disorder, and migraines. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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