Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Seribantumab (MM 121), a fully human IgG2 monoclonal antibody, specifically targets HER3, inhibiting the activation of the epidermal growth factor receptor (ErbB) family and its subsequent signaling. This action effectively blocks neuregulin 1 (NRG1) fusion-dependent tumorigenesis within in vitro and in vivo studies of patient-derived cancer models in breast, lung, and ovarian cancers [1].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | Inquiry |
Description | Seribantumab (MM 121), a fully human IgG2 monoclonal antibody, specifically targets HER3, inhibiting the activation of the epidermal growth factor receptor (ErbB) family and its subsequent signaling. This action effectively blocks neuregulin 1 (NRG1) fusion-dependent tumorigenesis within in vitro and in vivo studies of patient-derived cancer models in breast, lung, and ovarian cancers [1]. |
Molecular Weight | 143.2 (kDa) |
CAS No. | 1334296-12-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Seribantumab 1334296-12-6 inhibitor inhibit