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SCPI-3 is a potent and competitive inhibitor of mosquito sterol carrier protein-2 (SCP-2), with inhibition concentrations of AeSCP-2IC50 = 0.159 µM and AeSCP-xIC50 = 0.285 µM. It physiologically impacts cholesterol metabolism in cultured insect cells, showing an IC50 of 3.09 µM in Aag-2 cells. SCPI-1 exhibits insecticidal activity against Aedes aegypti, with an LD50 of 12.3 µM.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | SCPI-3 is a potent and competitive inhibitor of mosquito sterol carrier protein-2 (SCP-2), with inhibition concentrations of AeSCP-2IC50 = 0.159 µM and AeSCP-xIC50 = 0.285 µM. It physiologically impacts cholesterol metabolism in cultured insect cells, showing an IC50 of 3.09 µM in Aag-2 cells. SCPI-1 exhibits insecticidal activity against Aedes aegypti, with an LD50 of 12.3 µM. |
| Molecular Weight | 364.16 |
| Formula | C14H10BrN3O4 |
| Cas No. | 349561-46-2 |
| Smiles | O=N(=O)C1=CC=2ON=C(NC2C(OC)=C1)C=3C=CC(Br)=CC3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
| Size | Quantity | Unit Price | Amount | Operation |
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