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Anti-DLL3 Antibody

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Catalog No. T9901A-1463

Anti-DLL3 Antibody is a humanized monoclonal antibody targeting Delta-like ligand 3 (DLL3). DLL3 is specifically overexpressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas, with minimal expression in normal tissues. This antibody binds to the extracellular domain of DLL3 with high affinity and induces rapid internalization. It serves as a critical tool for developing targeted therapies, such as ADCs or bispecific antibodies, aimed at delivering payloads into tumor cells to induce apoptosis and inhibit tumor growth.

Anti-DLL3 Antibody

Anti-DLL3 Antibody

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Catalog No. T9901A-1463
Anti-DLL3 Antibody is a humanized monoclonal antibody targeting Delta-like ligand 3 (DLL3). DLL3 is specifically overexpressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas, with minimal expression in normal tissues. This antibody binds to the extracellular domain of DLL3 with high affinity and induces rapid internalization. It serves as a critical tool for developing targeted therapies, such as ADCs or bispecific antibodies, aimed at delivering payloads into tumor cells to induce apoptosis and inhibit tumor growth.
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Product Introduction

Bioactivity
Description
Anti-DLL3 Antibody is a humanized monoclonal antibody targeting Delta-like ligand 3 (DLL3). DLL3 is specifically overexpressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas, with minimal expression in normal tissues. This antibody binds to the extracellular domain of DLL3 with high affinity and induces rapid internalization. It serves as a critical tool for developing targeted therapies, such as ADCs or bispecific antibodies, aimed at delivering payloads into tumor cells to induce apoptosis and inhibit tumor growth.
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetDLL3
Chemical Properties
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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