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Anti-DLL3 Antibody is a humanized monoclonal antibody targeting Delta-like ligand 3 (DLL3). DLL3 is specifically overexpressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas, with minimal expression in normal tissues. This antibody binds to the extracellular domain of DLL3 with high affinity and induces rapid internalization. It serves as a critical tool for developing targeted therapies, such as ADCs or bispecific antibodies, aimed at delivering payloads into tumor cells to induce apoptosis and inhibit tumor growth.

| Description | Anti-DLL3 Antibody is a humanized monoclonal antibody targeting Delta-like ligand 3 (DLL3). DLL3 is specifically overexpressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas, with minimal expression in normal tissues. This antibody binds to the extracellular domain of DLL3 with high affinity and induces rapid internalization. It serves as a critical tool for developing targeted therapies, such as ADCs or bispecific antibodies, aimed at delivering payloads into tumor cells to induce apoptosis and inhibit tumor growth. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | DLL3 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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