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Apoptosis inducer 39
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Catalog No. T211764
Apoptosis inducer39 is an apoptosis inducer with IC50 values of 4.53 μM for MDA-MB-231 cells and 15.42 μM for A549 cells. It exhibits antitumor activity in vitro by reducing the expression of the anti-apoptotic protein Bcl-2 and increasing the expression of the pro-apoptotic protein Bax. Apoptosis inducer39 is applicable in breast cancer and non-small cell lung cancer research.
Apoptosis inducer 39
Apoptosis inducer 39
😃Good
Catalog No. T211764
Apoptosis inducer39 is an apoptosis inducer with IC50 values of 4.53 μM for MDA-MB-231 cells and 15.42 μM for A549 cells. It exhibits antitumor activity in vitro by reducing the expression of the anti-apoptotic protein Bcl-2 and increasing the expression of the pro-apoptotic protein Bax. Apoptosis inducer39 is applicable in breast cancer and non-small cell lung cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Apoptosis inducer39 is an apoptosis inducer with IC50 values of 4.53 μM for MDA-MB-231 cells and 15.42 μM for A549 cells. It exhibits antitumor activity in vitro by reducing the expression of the anti-apoptotic protein Bcl-2 and increasing the expression of the pro-apoptotic protein Bax. Apoptosis inducer39 is applicable in breast cancer and non-small cell lung cancer research. |
| In vitro | Apoptosis inducer 39 (Compound Y22) (5-40 μM, 0-24 h) reduces the number of MDA-MB-231 cells, causing cell shrinkage and the formation of apoptotic blebs. Additionally, Apoptosis inducer 39 (5-20 μM, 24 h) significantly inhibits cell migration and exerts anti-tumor effects by inducing apoptosis in MDA-MB-231 cells. |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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