Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethambutol is a bacteriostatic antimycobacterial agent obstructed the formation of cell wall by inhibiting arabinosyl transferases.
Pack Size | Availability | Price/USD | Quantity |
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500 mg | 6-8 weeks | Inquiry |
Description | Ethambutol is a bacteriostatic antimycobacterial agent obstructed the formation of cell wall by inhibiting arabinosyl transferases. |
In vitro | Ethambutol is effective against M. tuberculosis (H37Rv) with MIC of 0.5 μg/mL in vitro [2]. Ethambutol is efficient on treatment of mycobacterial-infected macrophages. When M. tuberculosis infected macrophages are treated with 6 μg/mL Ethambutol, the log CFUs following treatment for 3 days is 4.17, while value in control group is 4.8. The MICs for M. avium (MTCC 1723) and M. smegmatis (MTCC 6) are 15 μg/mL and 0.18 μg/mL, respectively. |
In vivo | Ethambutol is efficient in animal model. 100 mg/kg Ethambutol given orally 15 days post i.v. infection 1 ×/week for 5 weeks, induces a lower log CFU compared to untreatment (4.59 vs 5.07) [3]. |
Molecular Weight | 204.31 |
Formula | C10H24N2O2 |
CAS No. | 74-55-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Ethambutol 74-55-5 inhibitor inhibit