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Decylubiquinone
🥰Excellent
Catalog No. T27139Cas No. 55486-00-5
Alias 6-Decylubiquinone
Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting breast cancer growth and metastasis, enhancing mitochondrial function in synaptosomes, and inhibiting tumor-induced angiogenesis.
Decylubiquinone
🥰Excellent
Purity: 99.92%
Catalog No. T27139Alias 6-DecylubiquinoneCas No. 55486-00-5
Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting breast cancer growth and metastasis, enhancing mitochondrial function in synaptosomes, and inhibiting tumor-induced angiogenesis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $118 | In Stock | |
| 10 mg | $178 | In Stock | |
| 25 mg | $409 | In Stock | |
| 50 mg | $698 | In Stock |
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Purity:99.92%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting breast cancer growth and metastasis, enhancing mitochondrial function in synaptosomes, and inhibiting tumor-induced angiogenesis. |
| Targets&IC50 | HCT116 cells:45.84 μM, LoVo cells:28.11 μM |
| In vitro | After treating HCT116 and LoVo cells with different concentrations of Decylubiquinone for 96 h, Decylubiquinone significantly reduced the proliferation of HCT116 and LoVo cells in a dose-dependent manner. The IC50 values were 45.84 μM and 28.11 μM, respectively. [1] Decylubiquinone (50 μm) significantly increased the activity of the ETC complex in the synaptosome. [2] |
| In vivo | In mouse CRC CT26 cell xenotransplantation model, Decylubiquinone (5 mg/kg, 12 days) was intraperitoneally injected, and it was found that Decylubiquinone significantly reduced CRC growth. [1] |
| Synonyms | 6-Decylubiquinone |
| Molecular Weight | 322.44 |
| Formula | C19H30O4 |
| Cas No. | 55486-00-5 |
| Smiles | O=C1C(OC)=C(OC)C(=O)C(=C1C)CCCCCCCCCC |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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