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Mollicellin K

Catalog No. TN13478 Copy Product Info
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Mollicellin K is a benzophenone derivative isolated from Chaetomium brasiliense. It exhibits antibacterial activity against Mycobacterium tuberculosis, antimalarial activity against Plasmodium falciparum (IC50 = 1.2 μM), and antifungal activity against Candida albicans (IC50 = 1.2 μM). Additionally, Mollicellin K demonstrates cytotoxicity towards KB cells (IC50 = 1.9 μM), BC1 cells (IC50 = 6.8 μM), NCI-H187 cells (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. The minimum inhibitory concentration (MIC) for tuberculosis is 12.5 μM.

Mollicellin K

Copy Product Info
🥰Excellent
Catalog No. TN13478

Mollicellin K is a benzophenone derivative isolated from Chaetomium brasiliense. It exhibits antibacterial activity against Mycobacterium tuberculosis, antimalarial activity against Plasmodium falciparum (IC50 = 1.2 μM), and antifungal activity against Candida albicans (IC50 = 1.2 μM). Additionally, Mollicellin K demonstrates cytotoxicity towards KB cells (IC50 = 1.9 μM), BC1 cells (IC50 = 6.8 μM), NCI-H187 cells (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. The minimum inhibitory concentration (MIC) for tuberculosis is 12.5 μM.

Mollicellin K
Cas No. 1179374-63-0
Pack SizePriceUSA StockGlobal StockQuantity
10 mgInquiryInquiryInquiry
50 mgInquiryInquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Mollicellin K is a benzophenone derivative isolated from Chaetomium brasiliense. It exhibits antibacterial activity against Mycobacterium tuberculosis, antimalarial activity against Plasmodium falciparum (IC50 = 1.2 μM), and antifungal activity against Candida albicans (IC50 = 1.2 μM). Additionally, Mollicellin K demonstrates cytotoxicity towards KB cells (IC50 = 1.9 μM), BC1 cells (IC50 = 6.8 μM), NCI-H187 cells (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. The minimum inhibitory concentration (MIC) for tuberculosis is 12.5 μM.
Chemical Properties
Molecular Weight382.37
FormulaC21H18O7
Cas No.1179374-63-0
SmilesO=CC1=C(O)C=C(C=2C(=O)OC=3C(OC12)=CC(O)=C(C(=O)C=C(C)C)C3C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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