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YD23

Name: YD23
Brand: TargetMol
SKU: T77973
Price: 81 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77973Cas No. 2951015-29-3

Alias YD-23, YD 23

YD23 is a PROTAC that induces SMARCA2 degradation, has anticancer activity, and selectively inhibits the growth of SMARCA4 mutant lung cancer cells in vitro.

YD23

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Purity: 98.11%

Catalog No. T77973Alias YD-23, YD 23Cas No. 2951015-29-3

YD23 is a PROTAC that induces SMARCA2 degradation, has anticancer activity, and selectively inhibits the growth of SMARCA4 mutant lung cancer cells in vitro.

Pack Size	Price	Availability
1 mg	$81	In Stock
5 mg	$163	In Stock
10 mg	$263	In Stock
25 mg	$529	In Stock
50 mg	$849	In Stock

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Batch Information

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Purity:98.11%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	YD23 is a PROTAC that induces SMARCA2 degradation, has anticancer activity, and selectively inhibits the growth of SMARCA4 mutant lung cancer cells in vitro.
Synonyms	YD-23, YD 23

Chemical Properties

Molecular Weight	738.76
Formula	C₃₈H₃₉FN₈O₇
Cas No.	2951015-29-3
Smiles	O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOC4=CC=C(C=C4F)CN5CCN(C=6C=C(N=NC6N)C7=CC=CC=C7O)CC5)C3C2=O)CC1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble.

DMSO: 80 mg/mL (108.29 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3536 mL	6.7681 mL	13.5362 mL	67.6810 mL
5 mM	0.2707 mL	1.3536 mL	2.7072 mL	13.5362 mL
10 mM	0.1354 mL	0.6768 mL	1.3536 mL	6.7681 mL
20 mM	0.0677 mL	0.3384 mL	0.6768 mL	3.3840 mL
50 mM	0.0271 mL	0.1354 mL	0.2707 mL	1.3536 mL
100 mM	0.0135 mL	0.0677 mL	0.1354 mL	0.6768 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc